skin disease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
T0059	Diphenylpyraline hydrochloride	4-Diphenylmethoxy-1-methylpiperidine hydrochloride	Histamine Receptor
	Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re...		Histamine Receptor
T64337	PF-04745637	PF4745637,PF 4745637,PF 04745637,PF-4745637	TRP/TRPV Channel
	PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].		TRP/TRPV Channel
T4644	Tapinarof	GSK2894512,Benvitimod,WBI 1001	AhR , Aryl Hydrocarbon Receptor
	Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.		AhR , Aryl Hydrocarbon Receptor
T7725	Albaconazole	W 0027,UR-9825,UR9825,W-0027	P450 , Antifungal
	Albaconazole (W-0027) is a small molecule fungal cytochrome P450 family member 51 (fungal CYP51A1) inhibitor. It is used in the treatment of fungal infections, skin and musculoskeletal disorders, and can be used in the s...		P450 , Antifungal
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T3S0013	Ethyl trans-caffeate	Ethyl caffeate,Caffeic Acid Ethyl Ester	Others
	1. Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) has anti-inflammatory activity. 2. Ethyl trans-caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl trans-caffeate is a...		Others
T21074	Dexamethasone acetate	Dexamethasone 21-acetate monohydrate,Decadron-LA,Decadron
	Dexamethasone acetate is an adrenocortical steroid. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, asthma, severe allergies, chronic obstructive lung disease, bra...
T37853	Cholesteryl Lignocerate
	Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum. Cholesteryl lignocerate can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals bu...
T69303	Isoxsuprine Free Base
	Isoxsuprine Free Base is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplyi...
TN1235	3,4,5-Tricaffeoylquinic acid		TNF , Akt , HIV Protease
	3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor 4 expression-mediated activation of the Akt, ERK and N...		TNF , Akt , HIV Protease
TN4696	Odorinol		Antifection
	Odorine and odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. (+)-Odorinol exhibits strong antiviral activity against Ranikhet disease virus (RVD) in chick embryo.		Antifection
T76919	Barzolvolimab
	Barzolvolimab (CDX 0159), a humanized anti-KIT IgG1 monoclonal antibody, specifically and potently inhibits KIT activation by SCF, thereby reducing skin mast cells and disease activity in chronic inducible urticaria [1].
T37187	D-erythro/L-threo Lysosphingomyelin (d18:1)	D-erythro/L-threo Lysosphingomyelin (d18:1)
	Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins.1,2It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis...